Difference time between United States of America and Sao Tome and Principe in hours, minutes, and seconds is [ -5 hours ] with gregorian date today is Thursday 25th of December 2025 in American local time, Where the time now in United States of America is 20:29 PM and the time now in Sao Tome and Principe is 01:29 AM in Sao Tomean local time and the time comparison between United States of America and Sao Tome and Principe in greenwich time ( GMT ) where United States of America late for greenwich time ( GMT -04:00 ) while Sao Tome and Principe he has the same greenwich time ( GMT +00:00 ).