Difference time between Mexico and Sao Tome and Principe in hours, minutes, and seconds is [ -5 hours ] with gregorian date today is Wednesday 21st of October 2026 in Mexican local time, Where the time now in Mexico is 16:29 PM and the time now in Sao Tome and Principe is 21:29 PM in Sao Tomean local time and the time comparison between United Mexican States and Sao Tome and Principe in greenwich time ( GMT ) where Mexico late for greenwich time ( GMT -05:00 ) while Sao Tome and Principe he has the same greenwich time ( GMT +00:00 ).